We thank Dr Koh for his comments and agree that clinical practice guidelines should evolve as new knowledge becomes available. For example, a recent network meta-analysis of 42 blood pressure–lowering trials including 144 220 patients found significantly lower risks of all-cause mortality among participants who achieved systolic blood pressure 120 to 124 mm Hg in comparison with all other achieved systolic blood pressure groups including 130 to 134, 140 to 144, 150 to 154, or 160 mm Hg or more.¹ Specifically, randomized groups who achieved a mean systolic …

中文翻译：

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Bress等对有关“美国采用SPRINT（收缩压干预试验）强化血压治疗方案的潜在死亡避免和严重不良事件”的来信的答复：来自NHANES（国家健康与营养调查）的预测）”

我们感谢Koh博士的评论，并同意随着新知识的出现，临床实践指南应不断发展。例如，最近对包括144 220例患者在内的42项降压试验的网络荟萃分析发现，与其他所有达到收缩压的人相比，达到收缩压120到124 mm Hg的参与者的全因死亡率风险显着降低包括130到134、140到144、150到154或160 mm Hg或更大的组。¹具体来说，随机分组的患者达到了平均收缩期……