Cover Picture: Secondary Phosphine Oxide Preligands for Palladium-Catalyzed C–H (Hetero)Arylations: Efficient Access to Pybox Ligands (Adv. Synth. Catal. 18/2017),Advanced Synthesis & Catalysis

当前位置： X-MOL 学术 › Adv. Synth. Catal. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Cover Picture: Secondary Phosphine Oxide Preligands for Palladium-Catalyzed C–H (Hetero)Arylations: Efficient Access to Pybox Ligands (Adv. Synth. Catal. 18/2017)
Advanced Synthesis & Catalysis ( IF 4.4 ) Pub Date : 2017-09-18 04:10:15 , DOI: 10.1002/adsc.201701122
Debasish Ghorai _{1,

2} , Valentin Müller ₁ , Helena Keil ₃ , Dietmar Stalke ₃ , Giuseppe Zanoni ₂ , Boryslav A. Tkachenko ₄ , Peter R. Schreiner ₄ , Lutz Ackermann _{1,

2}

Affiliation

The inside cover picture, provided by Lutz Ackermann and co-workers, demonstrates the design of the novel palladium complex derived from a secondary bisdiamantyl phosphine oxide preligand that enables the facile activation of challenging C−H bonds of oxazolines without the need of directing groups. The user-friendly palladium catalyst also proved effective for synthetically useful heterocyclic electrophiles, which sets the stage for the step-economical synthesis of pybox ligands under racemization-free reaction conditions. Details of this study can be found in the full paper on pages 3137–3141 (D. Ghorai, V. Müller, H. Keil, D. Stalke, G. Zanoni, B. A. Tkachenko, P. R. Schreiner, L. Ackermann, Adv. Synth. Catal. 2017, 359, 3137–3141; DOI: 10.1002/adsc.201700663).

中文翻译：

封面图片：用于钯催化的C–H（杂）芳基的二级膦氧化物配位体：有效使用Pybox配体（高级合成，目录号18/2017）

由Lutz Ackermann及其同事提供的内页封面照片展示了衍生自仲双双金刚烷基氧化膦预配体的新型钯配合物的设计，该钯配合物可轻松活化恶唑啉的具有挑战性的C-H键而无需指挥基团。用户友好的钯催化剂还证明对合成有用的杂环亲电试剂有效，这为在无消旋反应条件下逐步经济地合成pybox配体奠定了基础。这项研究的详细信息可在3137-3141（D. Ghorai，五，米勒，凯尔H.，D. Stalke，G Zanoni，B. A.特卡琴科，P. R.兴农，L.阿克曼，页面的全部论文中找到进阶合成器。CATAL。2017，359，3137-3141; DOI：10.1002 / adsc.201700663）。

更新日期：2017-09-18

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11