Recent Advances in Nanogenerator‐Driven Self‐Powered Implantable Biomedical Devices,Advanced Energy Materials

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Recent Advances in Nanogenerator‐Driven Self‐Powered Implantable Biomedical Devices
Advanced Energy Materials ( IF 24.4 ) Pub Date : 2017-09-18 , DOI: 10.1002/aenm.201701210
M. A. Parvez Mahmud ₁ , Nazmul Huda ₁ , Shahjadi Hisan Farjana ₁ , Mohsen Asadnia ₁ , Candace Lang ₁

Affiliation

Implantable medical devices (IMDs) have experienced a rapid progress in recent years to the advancement of state‐of‐the‐art medical practices. However, the majority of this equipment requires external power sources like batteries to operate, which may restrict their application for in vivo situations. Furthermore, these external batteries of the IMDs need to be changed at times by surgical processes once expired, causing bodily and psychological annoyance to patients and rising healthcare financial burdens. Currently, harvesting biomechanical energy in vivo is considered as one of the most crucial energy‐based technologies to ensure sustainable operation of implanted medical devices. This review aims to highlight recent improvements in implantable triboelectric nanogenerators (iTENG) and implantable piezoelectric nanogenerators (iPENG) to drive self‐powered, wireless healthcare systems. Furthermore, their potential applications in cardiac monitoring, pacemaker energizing, nerve‐cell stimulating, orthodontic treatment and real‐time biomedical monitoring by scavenging the biomechanical power within the human body, such as heart beating, blood flowing, breathing, muscle stretching and continuous vibration of the lung are summarized and presented. Finally, a few crucial problems which significantly affect the output performance of iTENGs and iPENGs under in vivo environments are addressed.

中文翻译：

纳米发电机驱动的自供电植入式生物医学设备的最新进展

近年来，随着先进医疗实践的发展，植入式医疗器械（IMD）经历了飞速发展。但是，大多数此类设备需要外部电源（例如电池）才能运行，这可能会限制其在体内情况下的应用。此外，IMD的这些外部电池一旦到期就需要通过外科手术程序进行更换，从而给患者带来身体和心理上的烦恼，并增加医疗保健负担。当前，在体内收集生物力学能量被认为是确保植入式医疗设备可持续运行的最关键的基于能量的技术之一。这篇综述旨在重点介绍可植入摩擦电动纳米发电机（iTENG）和可植入压电纳米发电机（iPENG）的最新改进，以驱动自供电无线医疗系统。此外，它们通过清除人体内的生物力学力量，如心脏跳动，血液流动，呼吸，肌肉拉伸和持续振动，在心脏监测，起搏器激励，神经细胞刺激，正畸治疗和实时生物医学监测中的潜在应用总结并介绍了肺部。最后，解决了一些关键问题，这些问题在体内环境下会严重影响iTENG和iPENG的输出性能。总结并介绍了神经细胞刺激，正畸治疗和通过清除人体内的生物力学力量（例如心脏跳动，血液流动，呼吸，肌肉伸展和肺部持续振动）进行实时生物医学监测。最后，解决了一些关键问题，这些问题在体内环境下会严重影响iTENG和iPENG的输出性能。总结并介绍了神经细胞刺激，正畸治疗和通过清除人体内的生物力学力量（例如心脏跳动，血液流动，呼吸，肌肉伸展和肺部持续振动）进行实时生物医学监测。最后，解决了一些关键问题，这些问题在体内环境下会严重影响iTENG和iPENG的输出性能。

更新日期：2017-09-18

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