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Prediction of pathological response to neoadjuvant treatment in rectal cancer with a two-protein immunohistochemical score derived from stromal gene-profiling
Annals of Oncology ( IF 56.7 ) Pub Date : 2017-07-06 , DOI: 10.1093/annonc/mdx293
S. Gonçalves-Ribeiro , R. Sanz-Pamplona , A. Vidal , X. Sanjuan , N. Guillen Díaz-Maroto , A. Soriano , J. Guardiola , N. Albert , M. Martínez-Villacampa , I. López , C. Santos , J. Serra-Musach , R. Salazar , G. Capellà , A. Villanueva , D.G. Molleví

Preoperative chemoradiotherapy followed by surgical mesorectal resection is the standard of care for locally advanced rectal carcinomas. Yet, predicting that patients will respond to treatment remains an unmet clinical challenge.

中文翻译:

基于基质基因谱分析的两种蛋白质免疫组化评分预测直肠癌新辅助治疗的病理反应

术前放化疗后行直肠系膜切除术是局部晚期直肠癌的治疗标准。然而,预测患者将对治疗产生反应仍然是尚未解决的临床挑战。
更新日期:2017-09-18
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