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Evidence for a Mesothelial Origin of Body Cavity Effusion Lymphomas
Journal of the National Cancer Institute ( IF 9.9 ) Pub Date : 2017-03-23 , DOI: 10.1093/jnci/djx016
David Sanchez-Martin 1 , Thomas S. Uldrick 1 , Hyeongil Kwak 1 , Hidetaka Ohnuki 1 , Mark N. Polizzotto 1 , Christina M. Annunziata 1 , Mark Raffeld 1 , Kathleen M. Wyvill 1 , Karen Aleman 1 , Victoria Wang 1 , Vickie A. Marshall 1 , Denise Whitby 1 , Robert Yarchoan 1 , Giovanna Tosato 1
Affiliation  

Primary effusion lymphoma (PEL) is a Kaposi's sarcoma herpes virus (KSHV)–induced lymphoma that typically arises in body cavities of HIV-infected patients. PEL cells are often co-infected with Epstein-Barr virus (EBV). “PEL-like” lymphoma is a KSHV-unrelated lymphoma that arises in body cavities of HIV-negative patients. “PEL-like” lymphoma is sometimes EBV positive. The derivation of PEL/“PEL-like” cells is unclear.

中文翻译:

体腔积液淋巴瘤的间皮起源的证据

原发性渗出性淋巴瘤(PEL)是由卡波西氏肉瘤疱疹病毒(KSHV)诱导的淋巴瘤,通常发生在感染HIV的患者的体腔中。PEL细胞通常与爱泼斯坦-巴尔病毒(EBV)共同感染。“ PEL样”淋巴瘤是与KSHV不相关的淋巴瘤,出现在HIV阴性患者的体腔中。“ PEL样”淋巴瘤有时是EBV阳性。PEL /“类PEL”细胞的来源尚不清楚。
更新日期:2017-03-23
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