A diastereoselective synthesis of 6‐alkoxy piperidin‐3‐ones based on a novel Rh(II)‐catalyzed tandem cyclization of aliphatic N‐sulfonyl triazoles and alcohols is reported herein for the first time, which provides a facile entry into piperidinones bearing quaternary carbons at C4 or C5 position. By employing an external chiral alcohol, the asymmetric version of the reaction has been realized.

中文翻译：

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Rh（II）催化脂肪族N-磺酰基-1,2,3-三唑和醇的串联环化反应，合成6-烷氧基哌啶-3-酮

本文首次报道了基于脂肪族N-磺酰基三唑和醇的新型Rh（II）催化串联环化反应的6-烷氧基哌啶-3-酮的非对映选择性合成，这提供了一种轻松进入带有季碳的哌啶酮的方法。在C4或C5位置。通过使用外部手性醇，已经实现了反应的不对称形式。