Echinococcosis is a neglected zoonotic disease affecting over 1 million people worldwide at any given time. It is the leading cause of hospital admissions for parasitic diseases in Chile. We conducted a retrospective investigation of hospitalized cases to describe the epidemiological trends of echinococcosis in Chile. We also examined the potential environmental risk factors for echinococcosis hospitalization rates. Through nation-wide hospital discharge data, a total of 11,516 hospitalized patients with cystic echinococcosis were identified between January 2001 and December 2012. The mean age of hospitalization was 40 years, with notable gender difference in pediatric patients. The hospitalization rate was found to be overall steadily decreasing from 2001 (7.02 per 100,000) to 2012 (4.53 per 100,000) with a 5% decrease per year (rate ratio = 0.95 [95% CI: 0.94, 0.96]). The hospitalization rate was higher in the south of Chile compared to the north. Goat density and intermediate precipitation were found to be significantly positively associated with the hospitalization rate while annual average temperature was found to be significantly negatively associated with the hospitalization rate. Findings of this study indicate that echinococcosis is still an important public health burden in Chile related to interaction with livestock and climate. Efforts should be placed on targeted prevention measures for farmers and raising awareness of echinococcosis among health care workers.

棘球co虫病是一种被忽视的人畜共患病，在任何给定时间影响全球超过100万人。它是智利因寄生虫病住院的主要原因。我们对住院病例进行了回顾性调查，以描述智利包虫病的流行病学趋势。我们还检查了棘球虫病住院率的潜在环境危险因素。通过全国范围的出院数据，在2001年1月至2012年12月之间共鉴定了11,516例囊性包虫病患者。平均住院年龄为40岁，小儿患者的性别差异显着。发现住院率从2001年（每100000例7.02）到2012年（每100,000例4.53）稳步下降，每年下降5％（比率为0）。95 [95％CI：0.94，0.96]。智利南部的住院率高于北部。山羊密度和中间降水与住院率显着正相关，而年平均温度与住院率显着负相关。这项研究的结果表明，棘球菌病仍然是智利与牲畜和气候相互作用相关的重要公共卫生负担。应努力针对农民采取有针对性的预防措施，并提高医护人员对棘球菌病的认识。山羊密度和中间降水与住院率显着正相关，而年平均温度与住院率显着负相关。这项研究的结果表明，棘球菌病仍然是智利与牲畜和气候相互作用相关的重要公共卫生负担。应努力针对农民采取有针对性的预防措施，并提高医护人员对棘球菌病的认识。山羊密度和中间降水与住院率显着正相关，而年平均温度与住院率显着负相关。这项研究的结果表明，棘球菌病仍然是智利与牲畜和气候相互作用相关的重要公共卫生负担。应努力针对农民采取有针对性的预防措施，并提高医护人员对棘球菌病的认识。