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Why microfluidics? Merits and trends in chemical synthesis
Lab on a Chip ( IF 6.1 ) Pub Date : 2017-09-15 00:00:00 , DOI: 10.1039/c7lc00627f
Yong Liu 1, 2, 3, 4, 5 , Xingyu Jiang 1, 2, 3, 4, 5
Affiliation  

The intrinsic limitations of conventional batch synthesis have hindered its applications in both solving classical problems and exploiting new frontiers. Microfluidic technology offers a new platform for chemical synthesis toward either molecules or materials, which has promoted the progress of diverse fields such as organic chemistry, materials science, and biomedicine. In this review, we focus on the improved performance of microreactors in handling various situations, and outline the trend of microfluidic synthesis (microsynthesis, μSyn) from simple microreactors to integrated microsystems. Examples of synthesizing both chemical compounds and micro/nanomaterials show the flexible applications of this approach. We aim to provide strategic guidance for the rational design, fabrication, and integration of microdevices for synthetic use. We critically evaluate the existing challenges and future opportunities associated with this burgeoning field.

中文翻译:

为什么要使用微流体?化学合成的优点和趋势

常规批处理合成法的固有局限性阻碍了其在解决经典问题和开拓新领域方面的应用。微流体技术为分子或材料的化学合成提供了新的平台,促进了有机化学,材料科学和生物医学等各个领域的进步。在这篇综述中,我们关注微反应器在处理各种情况下的性能提高,并概述了从简单微反应器到集成微系统的微流体合成(微合成,μSyn)趋势。合成化合物和微米/纳米材料的示例显示了该方法的灵活应用。我们旨在为合理设计,制造和集成微型设备的合成用途提供战略指导。
更新日期:2017-09-15
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