Foodborne diseases caused by bacterial pathogens are severe threats to human health. Conventional culture based microbiologic methods for the analysis of bacterial contamination in food products are laborious, time consuming and require specific skills. Immunologic and polymerase chain reaction (PCR)-based molecular methods are also costly, lack specificity, and may yield false results. As outlined in this review, fluorescent nanobiosensors have now become effective alternative tools for rapid and routine detection of foodborne bacteria. We provide an overview of the use of different fluorescent nanomaterials in the development of nanobiosensors with special emphasis on underlying detection principles, sensitivity, specificity, and their capability of multiplexed analysis. In summary, the diverse nanomaterials used for bacterial detection are critically analyzed with respect to their advantages and limitations for future applications in the diagnosis of foodborne bacteria.

中文翻译：

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荧光纳米生物传感器用于食源性细菌的靶向检测

由细菌病原体引起的食源性疾病是对人类健康的严重威胁。用于分析食品中细菌污染的基于常规培养的微生物学方法费力，费时且需要特定技能。基于免疫学和聚合酶链反应（PCR）的分子方法也很昂贵，缺乏特异性，并可能产生错误的结果。如本评论所述，荧光纳米生物传感器现已成为用于快速常规检测食源性细菌的有效替代工具。我们提供了在纳米生物传感器开发中使用不同荧光纳米材料的概述，特别着重于潜在的检测原理，灵敏度，特异性及其多重分析能力。总之，