Precision medicine is defined as medical care that is designed to optimise diagnostic efficiency or therapeutic benefit by targeting the needs of individual patients on the basis of genetic, biomarker, phenotypic, or psychosocial characteristics.¹ Inherent to precision medicine is the goal of minimising unnecessary side-effects for individuals who are less likely to benefit from a particular treatment. The development of precision medicine for the treatment of obesity has distinct challenges. Available treatments for obesity and its comorbidities have large variations in efficacy in different individuals, and several pharmacological drugs have been linked to adverse responses and health risks.

中文翻译：

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精准医学：肥胖症的诊断和治疗

精密医学被定义为旨在根据基因，生物标志物，表型或社会心理特征针对个别患者的需求来优化诊断效率或治疗效益的医疗服务。¹精密医学固有的目标是将不太可能从特定治疗中受益的个体的不必要副作用减至最少。发展用于治疗肥胖症的精确医学具有明显的挑战。肥胖症及其合并症的可用治疗方法在不同个体中的疗效差异很大，并且几种药理学药物已与不良反应和健康风险联系在一起。