当前位置: X-MOL 学术Tetrahedron Lett. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Facile synthesis of α, β-unsaturated esters through a one-pot copper-catalyzed aerobic oxidation-Wittig reaction
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2017-09-14 , DOI: 10.1016/j.tetlet.2017.09.020
Cheng Ren , Zhenyu Shi , Weijie Ding , Zhiqing Liu , Huile Jin , Xiaochun Yu , Shun Wang

An efficient one-pot synthesis of α, β-unsaturated esters through the aerobic oxidation – Wittig tandem reaction of alcohols and phosphorous ylide is developed. This new method operates under mild reaction conditions, and uses CuI/TEMPO (TEMPO = 2,2,6,6-tetramethylpiperidine-N-oxyl) as co-catalyst and air (O2) as the oxidant. It tolerates a wide range of functionalized benzylic alcohol and aliphatic alcohols.



中文翻译:

通过一锅铜催化的好氧氧化-Wittig反应轻松合成αβ-不饱和酯

开发了一种有效的一锅法合成αβ-不饱和酯的方法,即通过醇与磷的叶立德的好氧氧化-Wittig串联反应。该新方法在温和的反应条件下运行,并使用CuI / TEMPO(TEMPO = 2,2,6,6-四甲基哌啶-N-氧基)作为助催化剂,并使用空气(O 2)作为氧化剂。它可以耐受各种官能化的苯甲醇和脂肪醇。

更新日期:2017-09-14
down
wechat
bug