Malignant pleural mesothelioma (MPM) is characterized by a bad prognosis and modest activity of systemic treatment. Currently, there is no clear agreement on the clinical role of second-line chemotherapy in patients with MPM; nevertheless, early case study reports including some pretreated patients had provided evidence that additional responses are possible with the use of further chemotherapy¹ after the failure of first-line treatment.

中文翻译：

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胸膜恶性间皮瘤二线治疗有空间吗？

恶性胸膜间皮瘤（MPM）的特点是预后差，全身治疗活动度低。目前，关于二线化疗在MPM患者中的临床作用尚无明确共识。但是，早期病例研究报告（包括一些接受过预处理的患者）提供了证据，表明在一线治疗失败后，进一步化疗¹可能会产生其他反应。