The replication vacuole of Legionella pneumophila makes contact with host mitochondria. In this issue of Cell Host & Microbe, Escoll et al. (2017) dissect the mechanisms of this interaction, the effect of the T4SS effector MitF on mitochondrial function, and the resultant metabolic reprogramming of infected cells to benefit the bacteria.

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碎片与征服

嗜肺军团菌的复制液泡与宿主线粒体接触。在本期《细胞宿主与微生物》中，Escoll等人。（2017）剖析了这种相互作用的机制，T4SS效应子MitF对线粒体功能的影响以及对感染细胞进行的新陈代谢重编程以使细菌受益。