Heart failure (HF) with preserved ejection fraction (HFpEF) is a clinical syndrome associated with poor quality of life, substantial health-care resource utilization, and premature mortality. We summarize the current knowledge regarding the epidemiology of HFpEF with a focus on community-based studies relevant to quantifying the population burden of HFpEF. Current data regarding the prevalence and incidence of HFpEF in the community as well as associated conditions and risk factors, risk of morbidity and mortality after diagnosis, and quality of life are presented. In the community, approximately 50% of patients with HF have HFpEF. Although the age-specific incidence of HF is decreasing, this trend is less dramatic for HFpEF than for HF with reduced ejection fraction (HFrEF). The risk of HFpEF increases sharply with age, but hypertension, obesity, and coronary artery disease are additional risk factors. After adjusting for age and other risk factors, the risk of HFpEF is fairly similar in men and women, whereas the risk of HFrEF is much lower in women. Multimorbidity is common in both types of HF, but slightly more severe in HFpEF. A majority of deaths in patients with HFpEF are cardiovascular, but the proportion of noncardiovascular deaths is higher in HFpEF than HFrEF.

中文翻译：

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射血分数保持不变的心力衰竭流行病学

保留射血分数（HFpEF）的心力衰竭（HF）是一种临床综合征，与生活质量差，大量医疗资源利用和过早死亡有关。我们总结了有关HFpEF流行病学的当前知识，重点是与量化HFpEF人口负担有关的基于社区的研究。提供了有关社区中HFpEF的患病率和发病率以及相关状况和危险因素，诊断后发病和死亡的风险以及生活质量的最新数据。在社区中，大约50％的HF患者患有HFpEF。尽管特定年龄段的HF发病率正在下降，但与没有射血分数（HFrEF）的HF相比，HFpEF的这种趋势并不那么严重。HFpEF的风险会随着年龄的增长而急剧增加，但是高血压，肥胖，和冠状动脉疾病是另外的危险因素。在调整了年龄和其他危险因素后，男性和女性的HFpEF风险相当相似，而女性的HFrEF风险则低得多。两种类型的HF均具有多发病率，但在HFpEF中则更为严重。HFpEF患者的大多数死亡是心血管疾病，但HFpEF的非心血管死亡比例高于HFrEF。