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Evaluation of a Rapid Molecular Drug-Susceptibility Test for Tuberculosis
The New England Journal of Medicine ( IF 96.2 ) Pub Date : 2017-09-13 , DOI: 10.1056/nejmoa1614915 Yingda L. Xie , Soumitesh Chakravorty , Derek T. Armstrong , Sandra L. Hall , Laura E. Via , Taeksun Song , Xing Yuan , Xiaoying Mo , Hong Zhu , Peng Xu , Qian Gao , Myungsun Lee , Jongseok Lee , Laura E. Smith , Ray Y. Chen , Joon Sung Joh , YoungSoo Cho , Xin Liu , Xianglin Ruan , Lili Liang , Nila Dharan , Sang-Nae Cho , Clifton E. Barry , Jerrold J. Ellner , Susan E. Dorman , David Alland
The New England Journal of Medicine ( IF 96.2 ) Pub Date : 2017-09-13 , DOI: 10.1056/nejmoa1614915 Yingda L. Xie , Soumitesh Chakravorty , Derek T. Armstrong , Sandra L. Hall , Laura E. Via , Taeksun Song , Xing Yuan , Xiaoying Mo , Hong Zhu , Peng Xu , Qian Gao , Myungsun Lee , Jongseok Lee , Laura E. Smith , Ray Y. Chen , Joon Sung Joh , YoungSoo Cho , Xin Liu , Xianglin Ruan , Lili Liang , Nila Dharan , Sang-Nae Cho , Clifton E. Barry , Jerrold J. Ellner , Susan E. Dorman , David Alland
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This investigational assay accurately detected M. tuberculosis mutations associated with resistance to isoniazid, fluoroquinolones, and aminoglycosides and holds promise as a rapid point-of-care test to guide therapeutic decisions for patients with tuberculosis. (Funded by the National Institute of Allergy and Infectious Diseases, National Institutes of Health, and the Ministry of Science and Technology of China; ClinicalTrials.gov number, NCT02251327.)
更新日期：2017-09-14
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