Development of risk reduction behavioral counseling for Ebola virus disease survivors enrolled in the Sierra Leone Ebola Virus Persistence Study, 2015-2016,PLOS Neglected Tropical Diseases

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Development of risk reduction behavioral counseling for Ebola virus disease survivors enrolled in the Sierra Leone Ebola Virus Persistence Study, 2015-2016
PLOS Neglected Tropical Diseases ( IF 3.4 ) Pub Date : 2017-09-11 , DOI: 10.1371/journal.pntd.0005827
Neetu Abad ₁ , Tasneem Malik ₂ , Archchun Ariyarajah ₃ , Patricia Ongpin ₄ , Matthew Hogben ₁ , Suzanna L R McDonald ₃ , Jaclyn Marrinan ₃ , Thomas Massaquoi ₅ , Anna Thorson ₆ , Elizabeth Ervin ₇ , Kyle Bernstein ₈ , Christine Ross ₉ , William J Liu _{10,

11} , Karen Kroeger ₁ , Kara N Durski ₁₂ , Nathalie Broutet ₆ , Barbara Knust ₇ , Gibrilla F Deen ₁₃ ,

Affiliation

Social & Behavioral Research and Evaluation Branch, Division of Sexually Transmitted Disease Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, & TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Office of Global Activities, Division of Sexually Transmitted Disease Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, & TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Comprehensive Care & Support for EVD Survivors, EVD Research, World Health Organization, Freetown, Sierra Leone.
Strategic information, Joint United Nations Programme on HIV/AIDS, Freetown, Sierra Leone.
Military Hospital 34, Sierra Leone Ministry of Defence, Freetown, Sierra Leone.
Department of Reproductive Health and Research, Family, Women's and Children's Health, World Health Organization, Geneva, Switzerland.
Viral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Epidemiology and Statistics Branch, Division of Sexually Transmitted Disease Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, & TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
HIV Care and Treatment Branch, Division of Global HIV/AIDS and Tuberculosis, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China.
Sierra Leone-China Friendship Biological Safety Laboratory, Chinese Center for Disease Control and Prevention, Freetown, Sierra Leone.
Pandemic and Epidemic Disease Department, Outbreaks and Health Emergencies, World Health Organization, Geneva, Switzerland.
Connaught Hospital; Sierra Leone Ministry of Health and Sanitation, Freetown, Sierra Leone.

Background

During the 2014–2016 West Africa Ebola Virus Disease (EVD) epidemic, the public health community had concerns that sexual transmission of the Ebola virus (EBOV) from EVD survivors was a risk, due to EBOV persistence in body fluids of EVD survivors, particularly semen. The Sierra Leone Ebola Virus Persistence Study was initiated to investigate this risk by assessing EBOV persistence in numerous body fluids of EVD survivors and providing risk reduction counseling based on test results for semen, vaginal fluid, menstrual blood, urine, rectal fluid, sweat, tears, saliva, and breast milk. This publication describes implementation of the counseling protocol and the key lessons learned.

Methodology/Principal findings

The Ebola Virus Persistence Risk Reduction Behavioral Counseling Protocol was developed from a framework used to prevent transmission of HIV and other sexually transmitted infections. The framework helped to identify barriers to risk reduction and facilitated the development of a personalized risk-reduction plan, particularly around condom use and abstinence. Pre-test and post-test counseling sessions included risk reduction guidance, and post-test counseling was based on the participants’ individual test results. The behavioral counseling protocol enabled study staff to translate the study’s body fluid test results into individualized information for study participants.

Conclusions/Significance

The Ebola Virus Persistence Risk Reduction Behavioral Counseling Protocol provided guidance to mitigate the risk of EBOV transmission from EVD survivors. It has since been shared with and adapted by other EVD survivor body fluid testing programs and studies in Ebola-affected countries.

中文翻译：

为 2015-2016 年参加塞拉利昂埃博拉病毒持久性研究的埃博拉病毒病幸存者开发降低风险的行为咨询

背景

在 2014-2016 年西非埃博拉病毒病 (EVD) 流行期间，公共卫生界担心埃博拉病毒 (EBOV) 从 EVD 幸存者的性传播是一种风险，因为 EBOV 在 EVD 幸存者的体液中持续存在，特别是精液。塞拉利昂埃博拉病毒持久性研究旨在通过评估埃博拉病毒病幸存者众多体液中的 EBOV 持久性来调查这种风险，并根据精液、阴道液、经血、尿液、直肠液、汗液、眼泪的检测结果提供风险降低咨询、唾液和母乳。本出版物描述了咨询方案的实施和主要经验教训。

方法论/主要发现

埃博拉病毒持续性风险降低行为咨询协议是根据用于预防 HIV 和其他性传播感染传播的框架开发的。该框架有助于确定降低风险的障碍，并促进制定个性化的降低风险计划，特别是在安全套使用和禁欲方面。测试前和测试后咨询包括降低风险指导，测试后咨询基于参与者的个人测试结果。行为咨询协议使研究人员能够将研究的体液测试结果转化为研究参与者的个性化信息。