Impedance Sensor to Detect Substance Change at the Needle Tip,Electroanalysis

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Impedance Sensor to Detect Substance Change at the Needle Tip
Electroanalysis ( IF 2.7 ) Pub Date : 2017-08-17 , DOI: 10.1002/elan.201700306
Lisa Helen ₁ , Brian D. O'Donnell ₂ , Walter Messina ₁ , Conor O'Mahony ₃ , Osman M. A. Ahmed ₄ , Eric J. Moore ₁

Affiliation

Objective, reliable, accurate and cost-effective methods for real-time needle localization within the body are needed for many different clinical applications. Electrical impedance (EI) is a technique used to identify biological tissues and has the potential to provide real-time needle localization during medical procedures. We have developed a needle integrated with an impedance sensor to enable needle tip impedance measurement and tissue identification. This paper details device performance as it traversed test media, gelatine and lard, at constant speeds and provides analysis of the impedance measurements taken from the needle tip. The average needle speed of forward advancement during ultrasound guided peripheral nerve block was defined and used in these experiments as a clinically relevant needle speed. Impedance was also recorded while the needle was static in bulks of the different substances. Physical change of substance at the needle tip was compared to a change in magnitude of impedance. A delay between the physical substance change and indication of a substance change by impedance was observed. On further investigation using impedance data recorded while the needle was static, limitations of current electrochemical analysers and software were identified as the cause for the delay. Impedance measured by the needle tip electrode accurately determined a change in substance. We conclude that this technology can feasibly provide data to inform substance type at the needle tip. An application in medical procedures will subsequently be evaluated.

中文翻译：

用于检测针尖物质变化的阻抗传感器

许多不同的临床应用都需要客观、可靠、准确和具有成本效益的体内实时针定位方法。电阻抗 (EI) 是一种用于识别生物组织的技术，具有在医疗过程中提供实时针定位的潜力。我们开发了一种与阻抗传感器集成的针头，以实现针尖阻抗测量和组织识别。本文详细介绍了设备以恒定速度穿过测试介质、明胶和猪油时的性能，并提供了对针尖阻抗测量值的分析。在超声引导的周围神经阻滞期间向前推进的平均针速被定义并在这些实验中用作临床相关的针速。当针在大量不同物质中静止时，阻抗也被记录下来。将针尖处物质的物理变化与阻抗大小的变化进行比较。观察到物理物质变化和通过阻抗指示物质变化之间的延迟。在使用针静止时记录的阻抗数据进行进一步调查时，当前电化学分析仪和软件的局限性被确定为延迟的原因。针尖电极测量的阻抗准确地确定了物质的变化。我们得出的结论是，这项技术可以提供可行的数据来告知针尖处的物质类型。随后将评估医疗程序中的应用程序。将针尖处物质的物理变化与阻抗大小的变化进行比较。观察到物理物质变化和通过阻抗指示物质变化之间的延迟。在使用针静止时记录的阻抗数据进行进一步调查时，当前电化学分析仪和软件的局限性被确定为延迟的原因。针尖电极测量的阻抗准确地确定了物质的变化。我们得出的结论是，这项技术可以提供可行的数据来告知针尖处的物质类型。随后将评估医疗程序中的应用程序。将针尖处物质的物理变化与阻抗大小的变化进行比较。观察到物理物质变化和通过阻抗指示物质变化之间的延迟。在使用针静止时记录的阻抗数据进行进一步调查时，当前电化学分析仪和软件的局限性被确定为延迟的原因。针尖电极测量的阻抗准确地确定了物质的变化。我们得出的结论是，这项技术可以提供可行的数据来告知针尖处的物质类型。随后将评估医疗程序中的应用程序。在使用针静止时记录的阻抗数据进行进一步调查时，当前电化学分析仪和软件的局限性被确定为延迟的原因。针尖电极测量的阻抗准确地确定了物质的变化。我们得出的结论是，这项技术可以提供可行的数据来告知针尖处的物质类型。随后将评估医疗程序中的应用程序。在使用针静止时记录的阻抗数据进行进一步调查时，当前电化学分析仪和软件的局限性被确定为延迟的原因。针尖电极测量的阻抗准确地确定了物质的变化。我们得出的结论是，这项技术可以提供可行的数据来告知针尖处的物质类型。随后将评估医疗程序中的应用程序。

更新日期：2017-08-17

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