AbstractThe authors describe an optical assay for determination of mercury(II) ion by making use of gold nanorods (AuNRs) which are found to aggregate after addition of 6-mercaptopurine (6-MP) by forming a covalent Au-S bond. Aggregation is accompanied by a color change to blue. However, the 6-MP induced aggregation is inhibited in the presence of Hg(II) results because of the formation of a more stable Hg-S bond. The different degrees of aggregation of the AuNRs is indicated by variations in the absorption spectra and accompanied by a color change from blue to brown. Under the optimal conditions, the ratio of absorbances at 780 and 665 nm varies in the 1–100 nM Hg(II) concentration range. The effect can also be detected with bare eyes. The limit of detection is 0.48 nM. The method is rapid, sensitive, and does not require sophisticated instrumentation. It was successfully applied to the determination of Hg(II) in spiked water samples. Graphical abstractSchematic of colorimetric determination of Hg2+ based on the inhibition of the aggregation of gold nanorods caused by 6-mercaptopurine. This method is sensitive with a 0.48 nM detection limit.

中文翻译：

---

基于抑制涂有 6-巯基嘌呤的金纳米棒聚集的汞 (II) 比色测定

摘要作者描述了一种利用金纳米棒 (AuNRs) 测定汞 (II) 离子的光学测定法，金纳米棒 (AuNRs) 在加入 6-巯基嘌呤 (6-MP) 后通过形成共价 Au-S 键而聚集。聚集伴随着颜色变为蓝色。然而，由于形成了更稳定的 Hg-S 键，6-MP 诱导的聚集在 Hg(II) 结果的存在下受到抑制。AuNRs 的不同聚集程度由吸收光谱的变化表明，并伴随着从蓝色到棕色的颜色变化。在最佳条件下，780 和 665 nm 处的吸光度比在 1–100 nM Hg(II) 浓度范围内变化。这种效果也可以用肉眼检测到。检测限为 0.48 nM。该方法快速、灵敏、并且不需要复杂的仪器。成功应用于加标水样中Hg(II)的测定。图形摘要基于抑制 6-巯基嘌呤引起的金纳米棒聚集的 Hg2+ 比色测定示意图。该方法灵敏，检测限为 0.48 nM。