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A wound-healing program is hijacked to promote cancer metastasis
Journal of Experimental Medicine ( IF 12.6 ) Pub Date : 2017-09-13 , DOI: 10.1084/jem.20171556
Leif W Ellisen 1
Affiliation  

In this issue of JEM, Sundaram et al. (https://doi.org/10.1084/jem.20170354) report a mechanism by which the normal epithelial wound healing response is “hijacked” to promote invasion and metastasis in head and neck squamous carcinomas (HNSCCs), a finding that unveils new markers of poor outcomes and potential targets for therapeutic intervention.



中文翻译:


伤口愈合程序被劫持以促进癌症转移



在本期 JEM 中,Sundaram 等人。 ( https://doi.org/10.1084/jem.20170354 )报告了一种机制,通过这种机制,正常的上皮伤口愈合反应被“劫持”,以促进头颈鳞状癌(HNSCC)的侵袭和转移,这一发现揭示了不良结果的新标志物和治疗干预的潜在目标。

更新日期:2017-09-13
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