In situ synthesis of NIR-light emitting carbon dots derived from spinach for bio-imaging applications,Journal of Materials Chemistry B

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In situ synthesis of NIR-light emitting carbon dots derived from spinach for bio-imaging applications
Journal of Materials Chemistry B ( IF 6.1 ) Pub Date : 2017-08-08 00:00:00 , DOI: 10.1039/c7tb00634a
Liping Li _{1,

2,

3,

4,

5} , Ruiping Zhang _{6,

7,

8,

9,

10} , Chunxiang Lu _{1,

2,

3,

4,

5} , Jinghua Sun _{4,

5,

11} , Lingjie Wang _{4,

5,

11} , Botao Qu _{4,

5,

11} , Tingting Li _{4,

5,

11} , Yaodong Liu _{1,

2,

3,

4,

5} , Sijin Li _{4,

5,

12}

Affiliation

Near infrared (NIR)-light emitting fluorescent probes have attracted extensive research attention in the bioimaging field due to their deep tissue penetration, minimal auto-fluorescence and lower emission light damage to bio-tissues. Herein, we designed and prepared NIR-light emitting CDs (R-CDs) from spinach by a one-step solvothermal method. The R-CDs exhibited good water solubility, a maximum fluorescence emission peak at 680 nm, a high quantum yield of 15.34%, remarkable photo-stability and resistance to metal ions in a body-simulating environment, excellent compatibility, negligible toxicity, and superior labelling capability in vitro and in vivo. These findings significantly highlight the design of NIR-light emitting CDs and exploit their bio-imaging applications.

中文翻译：

原位合成菠菜的近红外发光碳点用于生物成像应用

由于近红外（NIR）发光荧光探针具有深厚的组织穿透力，最小的自发荧光和对生物组织的较低损伤，因此在生物成像领域引起了广泛的研究关注。在本文中，我们通过一步溶剂热法从菠菜中设计并制备了NIR发光CD（R-CD）。R-CDs表现出良好的水溶性，在680 nm处的最大荧光发射峰，15.34％的高量子产率，在人体模拟环境中显着的光稳定性和对金属离子的抵抗力，出色的相容性，可忽略的毒性以及优异的体外和体内标记能力。这些发现显着突出了NIR发光CD的设计并利用了其生物成像应用。

更新日期：2017-09-13

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