Six new phenylethanoid glycosides possessing dioxane moieties, named forsyoxasides A−F (1–6), together with four known such compounds (7–10) were isolated from the fruits of Forsythia suspensa. These structures were illustrated by extensive NMR spectroscopic techniques and by comparing their NMR data with the related literatures. Notably, forsyoxaside A (1) is a novel dioxane phenylethanoid glycoside with an axial aromatic ring, which is rare in the natural sources. Compounds 1, 4, 7 and 8 showed remarkable bioactivities against rotenone induced PC12 cell damage. Furthermore, 1 and 7 displayed strong activities against serum deprivation induced damage on the same cells.

从连翘果实中分离出六个具有二恶烷基团的新苯乙醛糖苷，名为甲酸（Forsyoxasides ）（1-6），以及四个已知的此类化合物（7-10）。通过广泛的NMR光谱技术并通过将其NMR数据与相关文献进行比较来说明这些结构。值得注意的是，虫草苷A（1）是一种具有轴向芳香环的新型二恶烷苯乙醛糖苷，在自然来源中很少见。化合物1，4，7和8表现出抵抗鱼藤酮诱导的PC12细胞的损伤显着的生物活性。此外，1和7 在对抗血清剥夺引起的相同细胞损伤方面显示出强大的活性。