Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis.,The Lancet

当前位置： X-MOL 学术 › Lancet › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis.
The Lancet ( IF 98.4 ) Pub Date : 2017-10-01 , DOI: 10.1016/s1474-4422(17)30278-8
Axel Petzold ₁ , Laura J Balcer ₂ , Peter A Calabresi ₃ , Fiona Costello ₄ , Teresa C Frohman ₅ , Elliot M Frohman ₅ , Elena H Martinez-Lapiscina ₆ , Ari J Green ₇ , Randy Kardon ₈ , Olivier Outteryck ₉ , Friedemann Paul ₁₀ , Sven Schippling ₁₁ , Patrik Vermersch ₁₂ , Pablo Villoslada ₆ , Lisanne J Balk ₁₃ ,

Affiliation

Moorfields Eye Hospital, London, UK; Department of Neurology, Amsterdam Neuroscience, VUmc MS Center Amsterdam and Dutch Expertise Centre for Neuro-ophthalmology, VU University Medical Center, Amsterdam, Netherlands; Institute of Neurology, University College London, London, UK.
Department of Neurology, Department of Ophthalmology, and Department of Population Health, New York University School of Medicine, New York, NY, USA.
Department of Neurology, Johns Hopkins Hospital, Baltimore, MD, USA.
Department of Clinical Neurosciences and Department of Surgery, University of Calgary, Calgary, AB, Canada.
Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Center of Neuroimmunology, Institute of Biomedical Research August Pi Sunyer, Hospital Clinic of Barcelona, Barcelona, Spain.
Multiple Sclerosis Center, Department of Neurology, University of California San Francisco, San Francisco, CA, USA.
Iowa City VA Center for Prevention and Treatment of Visual Loss, Department of Veterans Affairs Hospital Iowa City, and Department of Ophthalmology and Visual Sciences, University of Iowa Hospital and Clinics, Iowa City, IA, USA.
Department of Neurology, University of Lille Nord de France, Lille, France.
NeuroCure Clinical Research Center, Charité, Department of Neurology, Experimental and Clinical Research Center, Max Delbrueck Center for Molecular Medicine and Charité Universitätsmedizin Berlin, Berlin, Germany.
Neuroimmunology and Multiple Sclerosis Research Section, University Hospital Zurich, Zurich, Switzerland.
Université Lille, CHRU Lille, LYRIC-INSERM U995, FHU Imminent, Lille, France.
Department of Neurology, Amsterdam Neuroscience, VUmc MS Center Amsterdam and Dutch Expertise Centre for Neuro-ophthalmology, VU University Medical Center, Amsterdam, Netherlands.

Structural retinal imaging biomarkers are important for early recognition and monitoring of inflammation and neurodegeneration in multiple sclerosis. With the introduction of spectral domain optical coherence tomography (SD-OCT), supervised automated segmentation of individual retinal layers is possible. We aimed to investigate which retinal layers show atrophy associated with neurodegeneration in multiple sclerosis when measured with SD-OCT.

中文翻译：

多发性硬化症中的视网膜层分割：系统评价和荟萃分析。

结构性视网膜成像生物标志物对于多发性硬化症中炎症和神经变性的早期识别和监测非常重要。随着光谱域光学相干断层扫描 (SD-OCT) 的引入，单个视网膜层的监督自动分割成为可能。我们旨在研究当用 SD-OCT 测量时，哪些视网膜层显示出与多发性硬化症中的神经变性相关的萎缩。

更新日期：2017-09-12

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文