Active smoking in stable COPD subjects significantly increased eosinophil accumulation in the distal airspaces, but not in sputum or peripheral blood. Our findings support the need to investigate this cell-type as a potential driver of COPD symptomatology and progression.

中文翻译：

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SPIROMICS队列中当前患有慢性阻塞性肺疾病的吸烟者的肺泡嗜酸性粒细胞增多

在稳定的COPD患者中积极吸烟会显着增加远端空域中的嗜酸性粒细胞积累，但在痰液或外周血中却没有。我们的发现支持对研究这种细胞类型作为COPD症状和进展的潜在驱动因素的需求。