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Rates of hippocampal atrophy and presence of post-mortem TDP-43 in patients with Alzheimer's disease: a longitudinal retrospective study.
The Lancet ( IF 168.9 ) Pub Date : 2017-11-01 , DOI: 10.1016/s1474-4422(17)30284-3 Keith A Josephs , Dennis W Dickson , Nirubol Tosakulwong , Stephen D Weigand , Melissa E Murray , Leonard Petrucelli , Amanda M Liesinger , Matthew L Senjem , Anthony J Spychalla , David S Knopman , Joseph E Parisi , Ronald C Petersen , Clifford R Jack , Jennifer L Whitwell
The Lancet ( IF 168.9 ) Pub Date : 2017-11-01 , DOI: 10.1016/s1474-4422(17)30284-3 Keith A Josephs , Dennis W Dickson , Nirubol Tosakulwong , Stephen D Weigand , Melissa E Murray , Leonard Petrucelli , Amanda M Liesinger , Matthew L Senjem , Anthony J Spychalla , David S Knopman , Joseph E Parisi , Ronald C Petersen , Clifford R Jack , Jennifer L Whitwell
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Post-mortem studies have not identified an association between β-amyloid or tau and rates of hippocampal atrophy in patients with Alzheimer's disease. TAR DNA binding protein 43 (TDP-43) is another protein linked to Alzheimer's disease. We aimed to investigate whether hippocampal TDP-43 is associated with increased rates of hippocampal atrophy.
中文翻译：
阿尔茨海默氏病患者海马萎缩率和验尸后TDP-43的存在：一项纵向回顾性研究。
验尸研究尚未发现阿尔茨海默氏病患者的β-淀粉样蛋白或tau与海马萎缩率之间存在关联。TAR DNA结合蛋白43（TDP-43）是与阿尔茨海默氏病相关的另一种蛋白。我们旨在调查海马TDP-43是否与海马萎缩率增加相关。
更新日期：2017-09-12
中文翻译：
阿尔茨海默氏病患者海马萎缩率和验尸后TDP-43的存在：一项纵向回顾性研究。
验尸研究尚未发现阿尔茨海默氏病患者的β-淀粉样蛋白或tau与海马萎缩率之间存在关联。TAR DNA结合蛋白43（TDP-43）是与阿尔茨海默氏病相关的另一种蛋白。我们旨在调查海马TDP-43是否与海马萎缩率增加相关。
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