After asthma: redefining airways diseases.,The Lancet

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After asthma: redefining airways diseases.
The Lancet ( IF 98.4 ) Pub Date : 2017-09-11 , DOI: 10.1016/s0140-6736(17)30879-6
Ian D Pavord ₁ , Richard Beasley ₂ , Alvar Agusti ₃ , Gary P Anderson ₄ , Elisabeth Bel ₅ , Guy Brusselle ₆ , Paul Cullinan ₇ , Adnan Custovic ₈ , Francine M Ducharme ₉ , John V Fahy ₁₀ , Urs Frey ₁₁ , Peter Gibson ₁₂ , Liam G Heaney ₁₃ , Patrick G Holt ₁₄ , Marc Humbert ₁₅ , Clare M Lloyd ₇ , Guy Marks ₁₆ , Fernando D Martinez ₁₇ , Peter D Sly ₁₈ , Erika von Mutius ₁₉ , Sally Wenzel ₂₀ , Heather J Zar ₂₁ , Andy Bush ₂₂

Affiliation

Respiratory Medicine Unit, Nuffield Department of Medicine and NIHR Oxford Biomedical Research Centre, University of Oxford, UK.
Medical Research Institute of New Zealand, Wellington, New Zealand.
Respiratory Institute, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain; CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain.
Lung Health Research Centre, University of Melbourne, Melbourne, VIC, Australia.
Department of Respiratory Medicine, Academic Medical Center, University of Amsterdam, Netherlands.
Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium; Departments of Epidemiology and Respiratory Medicine, Erasmus Medical Center, Rotterdam, Netherlands.
National Heart and Lung Institute, Imperial College, London, UK.
Department of Paediatrics, Imperial College, London, UK.
Departments of Paediatrics and Social and Preventive Medicine, University of Montreal, Montreal, QC, Canada.
Cardiovascular Research Institute, and Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
University Children's Hospital Basel, University of Basel, Basel, Switzerland.
Department of Respiratory and Sleep Medicine, John Hunter Hospital, Hunter Medical Research Institute, Newcastle, NSW, Australia; Priority Research Centre for Asthma and Respiratory Disease, The University of Newcastle, Newcastle, NSW, Australia.
Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
Telethon Kids Institute, University of Western Australia, Perth, WA, Australia.
L'Université Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Paris, France; Service de Pneumologie, Hôpital Bicêtre, Paris, France; INSERM UMR-S 999, Hôpital Marie Lannelongue, Paris, France.
Department of Respiratory Medicine, South Western Sydney Clinical School, University of New South Wales, Sydney, NSW, Australia.
Asthma and Airway Disease Research Center, The University of Arizona, Tuscon, AZ, USA.
Department of Children's Health and Environment, Children's Health Queensland, Brisbane, QLD, Australia; Centre for Children's Health Research, Brisbane, QLD, Australia.
Dr. von Haunersches Kinderspital, Ludwig Maximilians Universität, Munich, Germany.
University of Pittsburgh Asthma Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Department of Paediatrics and Child Health, Red Cross Children's Hospital and Medical Research Council Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.
Department of Paediatrics, Imperial College, London, UK; Department of Paediatric Respiratory Medicine, Imperial College, London, UK.

Asthma is responsible for considerable global morbidity and health-care costs. Substantial progress was made against key outcomes such as hospital admissions with asthma and mortality in the 1990s and early 2000s, but little improvement has been observed in the past 10 years, despite escalating treatment costs. New assessment techniques are not being adopted and new drug discovery has progressed more slowly than in other specialties.

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