A practical approach for the synthesis of oxindole and isatin derivatives by Pd-catalyzed intramolecular amination,Organic Chemistry Frontiers

当前位置： X-MOL 学术 › Org. Chem. Front. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

A practical approach for the synthesis of oxindole and isatin derivatives by Pd-catalyzed intramolecular amination
Organic Chemistry Frontiers ( IF 4.6 ) Pub Date : 2017-09-05 00:00:00 , DOI: 10.1039/c7qo00710h
Yubo Pang _{1,

2,

3,

4,

5} , Mingyu Guan _{1,

2,

3,

4,

5} , Runsheng Zeng _{1,

2,

3,

4,

5} , Yingsheng Zhao _{1,

2,

3,

4,

5}

Affiliation

Oxindole/isatin-N-acetamide derivatives are a class of important pharmacologically active compounds. Herein, we report a practical protocol for the synthesis of such derivatives based on palladium-catalyzed intramolecular amination. Various functional groups are tolerated, and the corresponding products are obtained in moderate to good yields, highlighting the potential synthetic utility of this method.

中文翻译：