Biomimetic Artificial Basilar Membranes for Next‐Generation Cochlear Implants,Advanced Healthcare Materials

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Biomimetic Artificial Basilar Membranes for Next‐Generation Cochlear Implants
Advanced Healthcare Materials ( IF 10.0 ) Pub Date : 2017-09-11 , DOI: 10.1002/adhm.201700674
Jongmoon Jang ₁ , Jeong Hun Jang ₂ , Hongsoo Choi ₁

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Patients with sensorineural hearing loss can recover their hearing using a cochlear implant (CI). However, there is a need to develop next‐generation CIs to overcome the limitations of conventional CIs caused by extracorporeal devices. Recently, artificial basilar membranes (ABMs) are actively studied for next‐generation CIs. The ABM is an acoustic transducer that mimics the mechanical frequency selectivity of the BM and acoustic‐to‐electrical energy conversion of hair cells. This paper presents recent progress in biomimetic ABMs. First, the characteristics of frequency selectivity of the ABMs by the trapezoidal membrane and beam array are addressed. Second, to reflect the latest research of energy conversion technologies, ABMs using various piezoelectric materials and triboelectric‐based ABMs are discussed. Third, in vivo evaluations of the ABMs in animal models are discussed according to the target position for implantation. Finally, future perspectives of ABM studies for the development of practical hearing devices are discussed.

中文翻译：

用于下一代人工耳蜗的仿生人造基底膜

感音神经性听力丧失的患者可以使用人工耳蜗（CI）恢复听力。但是，有必要开发下一代CI，以克服由体外设备引起的常规CI的局限性。近年来，人们积极研究了下一代基底CI的人工基底膜（ABM）。ABM是一种声换能器，它模仿BM的机械频率选择性和毛细胞的声电能量转换。本文介绍了仿生反弹道导弹的最新进展。首先，解决了梯形膜和波束阵列对ABM的频率选择性特性。其次，为了反映能量转换技术的最新研究，讨论了使用各种压电材料的ABM和基于摩擦电的ABM。第三，根据植入的目标位置，讨论了动物模型中ABM的体内评估。最后，讨论了用于实际听力设备开发的ABM研究的未来前景。

更新日期：2017-09-11

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