In this issue of Cancer Cell, Bosse et al. report GPC2 as a therapeutic target in neuroblastoma. They show that GPC2 is selectively expressed on the cell surface of neuroblastoma and is a dependency in this disease. Moreover, they demonstrate the therapeutic potential of an antibody-drug conjugate targeting GPC2.

中文翻译：

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划伤神经母细胞瘤中免疫治疗靶标的表面。

在本期《癌细胞》中，Bosse等人。报告GPC2作为神经母细胞瘤的治疗靶标。他们表明，GPC2在神经母细胞瘤的细胞表面选择性表达，并且是这种疾病的依赖性。此外，它们证明了靶向GPC2的抗体-药物偶联物的治疗潜力。