Two new compounds heliotropiumides A (1) and B (2), phenolamides each with an uncommon carbamoyl putrescine moiety, were isolated from the seeds of a naturalized Hawaiian higher plant, Heliotropium foertherianum Diane & Hilger in the borage family, which is widely used for the treatment of ciguatera fish poisoning. The structures of compounds 1 and 2 were characterized based on MS spectroscopic and NMR analysis, and DP4+ calculations. The absolute configuration (AC) of compound 1 was determined by comparison of its optical rotation with those reported in literature. Compound 2 showed inhibition against NF-κB with an IC₅₀ value of 36 μM.

从琉璃苣家族的一个天然夏威夷高等植物Heliotropium foertherianum Diane＆Hilger的种子中分离出两种新的化合物Heliotropiumides A（1）和B（2），各自具有一个不常见的氨基甲酰基腐胺的酚酰胺。瓜gua鱼中毒的治疗。基于MS光谱和NMR分析以及DP4 +计算，对化合物1和2的结构进行了表征。通过将化合物1的旋光度与文献报道的旋光度进行比较来确定化合物1的绝对构型（AC）。化合物2的IC ₅₀表现出对NF-κB的抑制作用 值为36μM。