Cough can be a debilitating symptom of idiopathic pulmonary fibrosis (IPF) and is difficult to treat. PA101 is a novel formulation of sodium cromoglicate delivered via a high-efficiency eFlow nebuliser that achieves significantly higher drug deposition in the lung compared with the existing formulations. We aimed to test the efficacy and safety of inhaled PA101 in patients with IPF and chronic cough and, to explore the antitussive mechanism of PA101, patients with chronic idiopathic cough (CIC) were also studied.

中文翻译：

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在特发性肺纤维化和慢性咳嗽中吸入克罗格列酸钠钠（PA101）的新配方：一项随机，双盲，概念验证的2期试验。

咳嗽可能是特发性肺纤维化（IPF）的虚弱症状，难以治疗。PA101是一种通过高效eFlow雾化器输送的新型croggliate钠制剂，与现有制剂相比，它在肺部的药物沉积明显更高。我们旨在测试吸入性PA101在IPF和慢性咳嗽患者中的疗效和安全性，并探讨PA101的镇咳作用，并对慢性特发性咳嗽（CIC）患者进行了研究。