Although modified rabies viruses have emerged as a powerful tool for tracing the inputs to genetically defined populations of neurons, the toxicity of the virus has limited its utility. A recent study employed a self-inactivating rabies (SiR) virus that enables recording or manipulation of targeted neurons for months.

中文翻译：

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一种在 DNA 上留下痕迹的自杀狂犬病病毒


尽管经过修饰的狂犬病病毒已成为追踪基因定义的神经元群体输入的强大工具，但该病毒的毒性限制了其实用性。最近的一项研究采用了一种自失活狂犬病 (SiR) 病毒，可以对目标神经元进行数月的记录或操作。