Human genetics and stem cell biology have advanced neurobiology for neurodevelopmental psychiatric disorders. In this issue of Cell Stem Cell, Forrest et al. (2017) demonstrate that studying the landscape of open chromatin regions in stem cell-derived neurons helps functional interpretation of non-coding genetic variants associated with these diseases.

中文翻译：

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开放芝麻：开放染色质区域使非编码风险变量变亮。

人类遗传学和干细胞生物学对于神经发育性精神病具有先进的神经生物学。在本期《细胞干细胞》中，Forrest等人。（2017）证明，研究干细胞衍生的神经元中开放染色质区域的景观有助于功能解释与这些疾病相关的非编码遗传变异。