In a small phase Ib study in this issue of Cell, Ribas et al. report that the combination of intralesional injection of a modified human herpes simplex virus and systemic anti-PD-1 treatment resulted in a 62% response rate in patients with metastatic melanoma, accompanied by enhanced T cell infiltration in virus-injected lesions.

中文翻译：

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通过结合免疫疗法将感冒转化为热肿瘤。

Ribas等人在本期《细胞》杂志的小型Ib期研究中。报告指出，病灶内注射改良的人单纯疱疹病毒和全身性抗PD-1治疗相结合，可使转移性黑色素瘤患者的反应率达到62％，并伴随病毒注射病变中T细胞浸润的增强。