当前位置: X-MOL 学术Nat. Struct. Mol. Biol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Aging: rewiring the circadian clock
Nature Structural & Molecular Biology ( IF 12.5 ) Pub Date :  , DOI: 10.1038/nsmb.3461
Rika Ohkubo , Danica Chen

Aging: rewiring the circadian clock

Nature Structural & Molecular Biology, Published online: 7 September 2017; doi:10.1038/nsmb.3461

The robustness of the circadian clock deteriorates with aging. Two new studies show that aging reprograms the circadian transcriptome in a cell-type-dependent manner and that such rewiring can be reversed by caloric restriction.



中文翻译:

老化:重新布线生物钟

老化:重新布线生物钟

《自然结构与分子生物学》,在线发布:2017年9月7日;doi:10.1038 / nsmb.3461

昼夜节律时钟的鲁棒性会随着时间的流逝而变差。两项新的研究表明,衰老以细胞类型依赖的方式对昼夜节律转录组进行重新编程,并且这种重新布线可以通过热量限制来逆转。

更新日期:2017-09-07
down
wechat
bug