In the decade since Josep Dalmau described the first case series of anti-NMDA receptor encephalitis,¹ the cellular mechanisms that give rise to autoantibody-associated encephalitides have been defined ever more accurately. By contrast, how immune responses disrupt brain systems that control emotional behaviour, memory, movement, and consciousness remains largely unknown. Substantial overlap between the symptoms of autoimmune encephalitis and psychiatric and neurological conditions continues to pose challenges for the rapid diagnosis and treatment of this potentially fatal disorder.

中文翻译：

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功能连通性可以诊断与抗体相关的脑炎吗？

在这十年以来塞普达尔莫描述的第一病例系列抗NMDA受体脑炎，^1个即产生自身抗体相关的脑炎已经更精确地定义过的细胞机制。相比之下，免疫反应如何破坏控制情绪行为，记忆，运动和意识的大脑系统仍然未知。自身免疫性脑炎的症状与精神病和神经疾病之间的实质性重叠继续为快速诊断和治疗这种潜在致命性疾病构成挑战。