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Effectiveness of a Third Dose of MMR Vaccine for Mumps Outbreak Control
The New England Journal of Medicine ( IF 96.2 ) Pub Date : 2017-09-06 , DOI: 10.1056/nejmoa1703309
Cristina V. Cardemil , Rebecca M. Dahl , Lisa James , Kathleen Wannemuehler , Howard E. Gary , Minesh Shah , Mona Marin , Jacob Riley , Daniel R. Feikin , Manisha Patel , Patricia Quinlisk

Students who had received a third dose of MMR vaccine had a lower risk of mumps than did those who had received two doses, after adjustment for the number of years since the second dose. Students who had received a second dose of MMR vaccine 13 years or more before the outbreak had an increased risk of mumps. These findings suggest that the campaign to administer a third dose of MMR vaccine improved mumps outbreak control and that waning immunity probably contributed to propagation of the outbreak. (Funded by the Centers for Disease Control and Prevention.)

中文翻译:

第三剂MMR疫苗对腮腺炎暴发控制的有效性

在调整了第二次接种后的年数之后,第三次接种MMR疫苗的学生患腮腺炎的风险要比接受两次接种的学生低。在爆发前13年或更长时间接受第二剂MMR疫苗的学生患腮腺炎的风险增加。这些发现表明,给予第三剂MMR疫苗的运动改善了腮腺炎的暴发控制,免疫力的下降可能促进了暴发的传播。(由疾病预防控制中心资助。)
更新日期:2017-09-07
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