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Overall Survival Prediction and Usefulness of Second-Line Chemotherapy in Advanced Pancreatic Adenocarcinoma
Journal of the National Cancer Institute ( IF 9.9 ) Pub Date : 2017-04-04 , DOI: 10.1093/jnci/djx037
Angélique Vienot , Guillaume Beinse , Christophe Louvet , Louis de Mestier , Aurélia Meurisse , Francine Fein , Bruno Heyd , Denis Cleau , Christelle d’Engremont , Anne-Claire Dupont-Gossart , Zaher Lakkis , Christophe Tournigand , Olivier Bouché , Benoît Rousseau , Cindy Neuzillet , Franck Bonnetain , Christophe Borg , Dewi Vernerey

Background: In advanced pancreatic ductal adenocarcinoma (aPDAC), there is no consensual strategy for second-line chemotherapy (L2). Better discrimination of overall survival (OS) may help clinical decision-making. We aimed to predict OS from the beginning of L2 and to assess the benefit from chemotherapy among the identified risk groups.

中文翻译:

晚期胰腺腺癌的总生存预测和二线化疗的实用性。

背景:在晚期胰腺导管腺癌(aPDAC)中,尚无共识的二线化疗策略(L2)。更好地区分总体生存率(OS)可能有助于临床决策。我们的目标是从L2开始就预测OS,并评估已确定风险组中化疗的益处。
更新日期:2017-09-06
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