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Breast Cancer Survival of BRCA1/BRCA2 Mutation Carriers in a Hospital-Based Cohort of Young Women
Journal of the National Cancer Institute ( IF 9.9 ) Pub Date : 2017-03-09 , DOI: 10.1093/jnci/djw329
Marjanka K. Schmidt , Alexandra J. van den Broek , Rob A. E. M. Tollenaar , Vincent T. H. B. M. Smit , Pieter J. Westenend , Mariël Brinkhuis , Wolter J. W. Oosterhuis , Jelle Wesseling , Maryska L. Janssen-Heijnen , Jan J. Jobsen , Agnes Jager , Adri C. Voogd , Flora E. van Leeuwen , Laura J. van ’t Veer

Background: The primary aim of the study was to investigate prognosis and long-term survival in young breast cancer patients with a BRCA1 or BRCA2 germline mutation compared with noncarriers. The secondary aim was to investigate whether differences in survival originate from associations with tumor characteristics, second cancers, and/or treatment response.

中文翻译:

在医院为基础的年轻女性中,BRCA1 / BRCA2突变携带者的乳腺癌生存率

背景:该研究的主要目的是研究与非携带者相比具有BRCA1BRCA2种系突变的年轻乳腺癌患者的预后和长期生存。第二个目的是研究存活率的差异是否源于与肿瘤特征,继发性癌症和/或治疗反应的关联。
更新日期:2017-03-09
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