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Effects of CTGF Blockade on Attenuation and Reversal of Radiation-Induced Pulmonary Fibrosis
Journal of the National Cancer Institute ( IF 9.9 ) Pub Date : 2017-03-09 , DOI: 10.1093/jnci/djw339
Sebastian Bickelhaupt , Christian Erbel , Carmen Timke , Ute Wirkner , Monika Dadrich , Paul Flechsig , Alexandra Tietz , Johanna Pföhler , Wolfgang Gross , Peter Peschke , Line Hoeltgen , Hugo A. Katus , Hermann-Josef Gröne , Nils H. Nicolay , Rainer Saffrich , Jürgen Debus , Mark D. Sternlicht , Todd W. Seeley , Kenneth E. Lipson , Peter E. Huber

Background: Radiotherapy is a mainstay for the treatment of lung cancer that can induce pneumonitis or pulmonary fibrosis. The matricellular protein connective tissue growth factor (CTGF) is a central mediator of tissue remodeling.

中文翻译:

CTGF阻断对放射性肺纤维化衰减和逆转的影响

背景:放射疗法是治疗可诱发肺炎或肺纤维化的肺癌的主要手段。母细胞蛋白结缔组织生长因子(CTGF)是组织重塑的主要介质。
更新日期:2017-03-09
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