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Insight into immunocytes infiltrations in polymorphous light eruption
Biotechnology Advances ( IF 16.0 ) Pub Date : 2017-07-17 , DOI: 10.1016/j.biotechadv.2017.07.006
Dongyun Lei , Wenjuan Wu , Li Yang , Yan Li , Jiaqi Feng , Lechun Lyu , Li He

Polymorphous light eruption (PLE) which is one of the most common photodermatoses has been demonstrated to be immune-mediated disorder. Resistance to UV-induced immunosuppression resulting from differential immune cells infiltration and cytokines secretion has been highlighted in the pathogenesis of PLE. In this study, we reviewed differential patterns of immune cells infiltrations and cytokines secretion that may contribute to PLE occurrence and development.



中文翻译:

洞察多态性喷发中免疫细胞的浸润

多态性喷发(PLE)是最常见的光皮病之一,已被证明是免疫介导的疾病。在PLE的发病机理中已突出了对由差异免疫细胞浸润和细胞因子分泌引起的紫外线诱导的免疫抑制的抵抗力。在这项研究中,我们审查了可能有助于PLE发生和发展的免疫细胞浸润和细胞因子分泌的不同模式。

更新日期:2017-07-17
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