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Lung Alveolar Repair: Not All Cells Are Equal
Trends in Molecular Medicine ( IF 12.8 ) Pub Date : 2017-09-01 , DOI: 10.1016/j.molmed.2017.08.009
Charlotte H Dean 1 , Clare M Lloyd 1
Affiliation  

The lungs are capable of repair but the extent to which this occurs varies widely. Recent data indicate that, following injury, different progenitor cell populations can arise, depending on the molecular environment. In turn, these result in either normal or aberrant alveolar repair. Thus, a key question in lung regenerative medicine is how to maintain a ‘Goldilocks zone’ of repair.



中文翻译:

肺泡修复:并非所有细胞都是平等的

肺能够修复,但发生的程度差异很大。最近的数据表明,在损伤后,可能会出现不同的祖细胞群,这取决于分子环境。反过来,这些会导致正常或异常的肺泡修复。因此,肺再生医学的一个关键问题是如何维持修复的“金发姑娘区”。

更新日期:2017-09-01
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