Neoantigens arising from tumor-specific genomic alterations constitute authentic non-self antigens and represent a new class of targets for cancer immunotherapy. Recent reports on various vaccine platforms targeting neoantigens suggest a basis for precision therapies customized to each patient’s tumor mutational profile.

中文翻译：

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新抗原疫苗通过免疫原性测试

由肿瘤特异性基因组改变产生的新抗原构成了真正的非自身抗原，代表了癌症免疫疗法的一类新的靶标。有关针对新抗原的各种疫苗平台的最新报告为针对每个患者的肿瘤突变谱定制的精确疗法奠定了基础。