Bacterial species constituting the intestinal microbiota are implicated in maintenance of health but also pathogenesis of inflammatory disease. The compositional complexity of the microbiota and metabolic interdependencies of microbial species challenge our ability to attribute host responses to specific bacterial strains. Studies using gnotobiotic mice, however, are providing important insights.

中文翻译：

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哺乳动物免疫系统的微生物调节。

构成肠道菌群的细菌不仅与健康有关，而且与炎症性疾病的发病机理有关。微生物群的组成复杂性和微生物物种的代谢相互依赖性挑战了我们将宿主反应归因于特定细菌菌株的能力。然而，使用生gnoticbiotic小鼠的研究提供了重要的见解。