Infections caused by the bacterial pathogen Acinetobacter baumannii are a mounting concern for healthcare practitioners as widespread antibiotic resistance continues to limit therapeutic treatment options. The biological processes used by A. baumannii to cause disease are not well defined, but recent research has indicated that secreted proteins may play a major role. A variety of mechanisms have now been shown to contribute to protein secretion by A. baumannii and other pathogenic species of Acinetobacter, including a type II secretion system (T2SS), a type VI secretion system (T6SS), autotransporter, and outer membrane vesicles (OMVs). In this review, we summarize the current knowledge of secretion systems in Acinetobacter species, and highlight their unique aspects that contribute to the pathogenicity and persistence of these emerging pathogens.

细菌病原体鲍曼不动杆菌引起的感染引起医疗保健从业人员越来越多的关注，因为广泛的抗生素耐药性继续限制治疗方法的选择。鲍曼不动杆菌用于引起疾病的生物学过程尚未明确定义，但最近的研究表明，分泌的蛋白质可能起主要作用。多种机制现在被证明有助于蛋白质分泌鲍曼不动杆菌和其它致病物种的不动杆菌属，包括II型分泌系统（T2SS），一个VI型分泌系统（T6SS），自转运，和外膜囊泡（ OMV）。在这篇综述中，我们总结了目前分泌系统的知识不动杆菌属，并突出其独特的方面，这些方面有助于这些新兴病原体的致病性和持久性。