Triclosan, an antimicrobial additive widely used in personal care products, has caused the contamination of various aquatic environment. Biodegradation was proved to play a vital role in the treatment of triclosan in wastewater. However, there is limited information about the metabolic pathway. In this study, three common freshwater microalgae including Chlorella pyrenoidosa (C. pyrenoidosa), Desmodesmus sp., and Scenedesmus obliquus (S. obliquus) were applied to remove and biodegrade triclosan in aqueous culture medium. High removal rate up to 99.7% was observed during the treatment of 400 μg L⁻¹ triclosan by the three microalgae for 1 day. The removal of triclosan attributed to cellular uptake by C. pyrenoidosa, and biotransformation by Desmodesmus sp. and S. obliquus. Simultaneously, triclosan metabolites resulted from hydroxylation, reductive dechlorination, or ether bond cleavage and their conjugates produced through glucosylation and/or methylation were detected in the biodegradation samples. Metabolic pathway of triclosan by algae were firstly proposed in this work, shedding light on the environmental fate of triclosan.

中文翻译：

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三种不同微藻在水生环境中对三氯生的去除和代谢

三氯生（Triclosan）是一种广泛用于个人护理产品中的抗菌添加剂，已引起各种水生环境的污染。事实证明，生物降解在废水中三氯生的处理中起着至关重要的作用。但是，关于代谢途径的信息有限。在这项研究中，三个常见的淡水微藻，包括小球藻小球藻（C. pyrenoidosa），Desmodesmus sp。和Scendesmus obliquus（S。obliquus）被用于在水性培养基中去除三氯生并对其进行生物降解。在处理400μgL ^-1时观察到高达99.7％的高去除率三氯生经三个微藻处理1天。三氯生的去除归因于C. pyrenoidosa的细胞摄取和Desmodesmus sp。的生物转化。和S. obliquus。同时，在生物降解样品中检测到由羟基化，还原性脱氯或醚键裂解产生的三氯生代谢物，并检测了通过糖基化和/或甲基化产生的共轭物。这项工作首先提出了藻类对三氯生的代谢途径，从而阐明了三氯生的环境命运。