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TOR, the Gateway to Cellular Metabolism, Cell Growth, and Disease.
Cell ( IF 64.5 ) Pub Date : 2017-Sep-21 , DOI: 10.1016/j.cell.2017.08.019
John Blenis

Michael N. Hall is this year's recipient of the Lasker Basic Medical Research Award for the identification of the target of rapamycin, TOR. TOR is a master regulator of the cell's growth and metabolic state, and its dysregulation contributes to a variety of diseases, including diabetes, obesity, neurodegenerative disorders, aging, and cancer, making the TOR pathway an attractive therapeutic target.

中文翻译:

TOR,细胞代谢,细胞生长和疾病的门户。

迈克尔·N·霍尔(Michael N. Hall)因确定雷帕霉素(TOR)的靶标而获得了今年的拉斯克基础医学研究奖(Lasker Basic Medical Research Award)。TOR是细胞生长和代谢状态的主要调节剂,其失调会导致多种疾病,包括糖尿病,肥胖症,神经退行性疾病,衰老和癌症,从而使TOR途径成为有吸引力的治疗靶点。
更新日期:2017-09-06
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