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New calcium‐free Na2O–Al2O3–P2O5 bioactive glasses with potential applications in bone tissue engineering
Journal of the American Ceramic Society ( IF 3.5 ) Pub Date : 2017-09-20 , DOI: 10.1111/jace.15216
Oliwia Jeznach 1 , Marcin Gajc 1 , Karolina Korzeb 1 , Andrzej Kłos 1 , Krzysztof Orliński 1 , Ryszard Stępień 1 , Małgorzata Krok-Borkowicz 2 , Łucja Rumian 2 , Krzysztof Pietryga 2 , Katarzyna Reczyńska 2 , Elżbieta Pamuła 2 , Dorota A. Pawlak 1, 3
Affiliation  

Sodium aluminophosphate glasses were evaluated for their bone repair ability. The glasses belonging to the system 45Na2O–xAl2O3‐(55‐x)P2O5, with = (3, 5, 7, 10 mol%) were prepared by a melt‐quenching method. We assessed the effect of Al2O3 content on the properties of Na2O–Al2O3–P2O5 (NAP) glasses, which were characterized by density measurements, DSC analyses, solubility, bioactivity in simulated body fluid and cytocompatibility with MG‐63 cells. To the best of our knowledge, this is the first investigation of calcium‐free Na2O–Al2O3–P2O5 system glasses as bioactive materials for bone tissue engineering.

中文翻译:

新型无钙Na2O–Al2O3–P2O5生物活性玻璃在骨组织工程中的潜在应用

评价铝磷酸盐玻璃的骨修复能力。通过熔融淬火方法制备了属于系统45Na 2 O– x Al 2 O 3-(55‐ x)P 2 O 5的玻璃,其中 =(3、5、7、10 mol%)。我们评估了Al 2 O 3含量对Na 2 O–Al 2 O 3 –P 2 O 5性质的影响。(NAP)眼镜,其特征在于密度测量,DSC分析,溶解度,在模拟体液中的生物活性以及与MG-63细胞的细胞相容性。据我们所知,这是对无钙Na 2 O–Al 2 O 3 –P 2 O 5系统玻璃作为骨组织工程生物活性材料的首次研究。
更新日期:2017-09-20
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