Antimicrobial resistance (AMR) is an escalating public health crisis that kills patients, threatens national security, and reduces the safety of medical procedures essential to save and enhance lives. Many types of complex medical care can be complicated by serious infections and rely on the availability of safe, effective antimicrobial drugs. In the past 2 years, national and global leaders have united against this threat, making tangible progress. However, budget cuts of a historic magnitude proposed by the Trump administration now threaten to undo this progress, placing patients in grave danger.

The Centers for Disease Control and Prevention (CDC) estimates that at least 2 million persons in the United States acquire antibiotic-resistant infections each year, resulting in at least 23 000 deaths. Antibiotic resistance is estimated to cost our health system more than $20 billion annually (1). Approximately 700 000 deaths are attributable to AMR each year globally. By 2050, a total of 350 million cumulative deaths will likely be attributable to AMR if current trends continue (2), and multidrug-resistant tuberculosis will account for most of these deaths (3).

中文翻译：

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拟议中的美国资助削减了抗菌素耐药性的进展

抗菌素耐药性（AMR）是一种不断升级的公共卫生危机，杀死了患者，威胁了国家安全，并降低了挽救和改善生命所必需的医疗程序的安全性。许多类型的复杂医疗保健可能因严重感染而变得复杂，并依赖于安全，有效的抗菌药物的可用性。在过去的两年中，国家和全球领导人团结一致抵抗了这一威胁，取得了明显进展。然而，特朗普政府提议的历史性削减预算如今威胁着取消这一进展，使患者处于严重危险之中。

疾病控制与预防中心（CDC）估计，美国每年至少有200万人感染抗药性感染，导致至少23000例死亡。据估计，抗生素耐药性每年给我们的卫生系统造成的损失超过200亿美元（1）。全球每年约有70万人死于AMR。如果当前的趋势持续下去，到2050年，AMR可能总共造成3.5亿例死亡（2），耐多药结核病将占这些死亡的大部分（3）。