Despite available pharmacological and interventional therapies, refractory angina is a common and disabling clinical condition, and a major public health problem, which affects patients' quality-of-life, and has a significant impact upon health care resources. Persistent angina is common not only in patients who are not good candidates for revascularization, but also in patients following successful revascularization. Clearly, there is a need for additional treatment options for refractory angina beyond currently available pharmacological and interventional therapies. It is of pivotal importance, in this condition, to practice a patient-centred health assessment approach, measuring success of a new therapy by its effects on patients' symptoms, functional status, and quality-of-life, rather than hard clinical endpoints as used in clinical studies. The coronary sinus Reducer is a novel technology designed to reduce disabling symptoms and improve quality-of-life of patients suffering from refractory angina. This review serves to update the clinician as to current evidence and future perspectives of the optimal utilization of this innovative technology.

中文翻译：

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心绞痛患者的 Reducer 装置：机制、适应症和前景

尽管有药物和介入疗法，难治性心绞痛是一种常见且致残的临床疾病，是影响患者生活质量的重大公共卫生问题，并对医疗资源产生重大影响。持续性心绞痛不仅在不适合血运重建的患者中很常见，而且在成功血运重建后的患者中也很常见。显然，除了目前可用的药物和介入疗法之外，还需要针对难治性心绞痛的其他治疗选择。在这种情况下，实践以患者为中心的健康评估方法至关重要，通过新疗法对患者症状、功能状态和生活质量的影响来衡量其成功与否，而不是临床研究中使用的硬临床终点。冠状窦减速器是一项新技术，旨在减少难治性心绞痛患者的致残症状并改善其生活质量。本综述旨在为临床医生提供最新证据，了解最佳利用这一创新技术的当前证据和未来前景。