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Ascorbate Depletion Reduces TET2 Activity to Accelerate Leukemogenesis
Cancer Discovery ( IF 29.7 ) Pub Date : 2017-09-01 , DOI: 10.1158/2159-8290.cd-rw2017-167 American Association for Cancer Research
中文翻译:
抗坏血酸消耗减少TET2活性,以加速白血病的发生。
更新日期:2017-09-22
Cancer Discovery ( IF 29.7 ) Pub Date : 2017-09-01 , DOI: 10.1158/2159-8290.cd-rw2017-167 American Association for Cancer Research
Elevated ascorbate levels maintain TET2 activity in HSCs and decline with differentiation.
中文翻译:
抗坏血酸消耗减少TET2活性,以加速白血病的发生。
抗坏血酸水平升高可维持HSC中的TET2活性,并随着分化而下降。